Stress and Brain Development: I

Effects of Atorvastatin on the Hypertension-Induced Oxidative Stress in the Rat Brain

Background: It is well known that the development of brain oxidative stress is one of the most serious complications of arterial hypertension that evokes brain tissue damage. The aim of this study was to examine the effects of atorvastatin treatment (20 mg/kg/day), as an antioxidant, to prevent the brain tissue oxidative stress in the hypertensive (HTN) rats. Methods: Experiments were performed...

P25: Post-Traumatic Stress Disorder: A Case Report

Following exposure to a major traumatic event like Iran-Iraq war(1980-1988) various reaction occurs, some of which result in stress-related psychiatric disorder. We have briefly described one such case and used it to indicate some features of post-traumatic stress disorder. The patient, B.B, is a 54 years old man who has served in Iran-Iraq war operations for about 19 months. He expresses that ...

Editorial : Sustainable Development of Cognitive Science and Technology Ecosystem an Overview to the “Human Brain Project” as a Functioning Sample

Assessment of oxidative stress parameters of brain-derived neurotrophic factor heterozygous mice in acute stress model

Objective(s): Exposing to stress may be associated with increased production of reactive oxygen species (ROS). Therefore, high level of oxidative stress may eventually give rise to accumulation of oxidative damage and development of numerous neurodegenerative diseases. It has been presented that brain-derived neurotrophic factor (BDNF) supports neurons against various neurodegenerative conditio...

The Effects of L-arginine on the Hippocampus of Male Rat Fetuses under Maternal Stress

Introduction: Prenatal stress has deleterious effects on the development of the brain and is associated with behavioral and psychosocial problems in childhood and adulthood. This study aimed to determine the protective effect of L-arginine on fetal brain under maternal stress. Methods: Twenty pregnant Wistar rats (weighting 200-230 g) were randomly divided into 4 groups (n=5 for each group). T...

Protective effect of ginger on diazinon-induced brain toxicity

Background and objectives: Diazinon (DZN), an organophosphate insecticide, is widely used in agriculture. One of its deleterious effects is on neural systems. Diazinon with acetylcholinesterase activity and lipid peroxidation induces brain toxicity . Ginger, as a medicinal plant, has antioxidant and anti-imflammatory properties. The aim of present study was to evaluate...